Noninvasive prenatal testing (NIPT) : state of the art
نویسندگان
چکیده
منابع مشابه
Noninvasive prenatal testing (NIPT) for fetal trisomies in a routinely first-trimester screening
Results Results from chromosome selective sequencing were available from 253 cases of 255 cases. In two cases fetal cell fraction was below the minimal requirement of 4%. In this population of 255 cases we found euploid pregnancies in 250 cases and 5 aneuploid pregnancies: two trisomies 21, one trisomy 18, one triosmy 13 and one 45 XO. In 195 pregnant women, the performance of screening by comb...
متن کاملComments on Editorial: Has Noninvasive Prenatal Testing (NIPT) Come of Age?
Recent advances in genomic sequencing and bioinformatics have led to the development of noninvasive detection methods with detection rates approaching those obtained with amniocentesis and chorionic villus sampling (CVS) [1, 2]. Recently, a novel prenatal testing method has become available. This method, known as noninvasive prenatal testing (NIPT), is a molecular approach for assessing fetal a...
متن کاملISUOG consensus statement on the impact of non-invasive prenatal testing (NIPT) on prenatal ultrasound practice.
The emergence of effective cell-free fetal DNA-based techniques to screen for trisomy 21 and other aneuploidies has greatly expanded the range of prenatal tests available over the last few years. Non-invasive prenatal testing (NIPT) is rapidly being incorporated into prenatal care, thus changing the traditional approach to prenatal screening and diagnosis. However, although NIPT techniques are ...
متن کاملThe Evolution of Prenatal Diagnosis from Invasive Procedures to Non-invasive Prenatal Testing (NIPT)
Yuval Yaron1,2,*, and Rachel Michaelson-Cohen3,4 1Prenatal Genetic Diagnosis Unit, Genetic Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel 2Sackler Faculty of Medicine, Tel Aviv University, Israel 3Department of Obstetrics & Gynecology, Shaare Zedek Medical Center, Hebrew University of Jerusalem, Israel 4Medical Genetics Institute, Shaare Zedek Medical Center, Hebrew University of...
متن کاملNoninvasive prenatal testing: the future is now.
Prenatal detection of chromosome abnormalities has been offered for more than 40 years, first by amniocentesis in the early 1970s and additionally by chorionic villus sampling (CVS) in the early 1980s. Given the well-recognized association between increasing maternal age and trisomy,1-3 the primary utilization of prenatal testing has been by older mothers. This has drastically reduced the incid...
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ژورنال
عنوان ژورنال: Revue Medicale de Bruxelles
سال: 2019
ISSN: 0035-3639
DOI: 10.30637/2019.18-096